Study of passive carried transport of ascorbic acid trough liquid membrane

Abstract

In this work a physical chemistry of the transport of Ascorbic Acid (cis-, diol compound) through a hydrophobic liquid membrane (1,2- Diclhoroethane) carried by Phenylboronic acid was done by using a BLM (Bulk Liquid Membrane) connected to a continuous flow circuit. Initially the transport process was difficult to study due the fast oxidation of the Ascorbic Acid in aqueous solution. The influence of the source phase concentration, temperature and the carrier on the transport of Acid Ascorbic concentration against time was observed for this compound in the receiving phase. An increase of the transport rate was promoted by increasing the temperature. The effect of the carrier on the transport became distinct because in the absence of this molecule none significant transport through the hydrophobic membrane was observed. By using UV-Vis spectrophotometry, the kinetics of the Ascorbic Acid was studied in the real time and the results were obtained using multivariate methods (PLS). Theoretical calculations were performed to estimate the relative stability between the two molecular structure wich can be formed in the hydrophobic membrane during the transport.